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tostrivetobeamongthetop100inmyfieldhasalwaysbeenmyaspiration.forthematerializationofthisaspiration,ihavededicatedallmyenthusiasmandenergytomyacademicendeavors—bothmystudiesandresearch—overthepastfewyears.however,tomydismay,theunsatisfactoryresearchconditionsinchinahavecausedtheresearchandthetherapeuticlevelinthefieldofmyspecialization,namelyclinicalmedicine/gastroenterology,tolagbehindthoseofthedevelopedcountriesinthewestbyatleast10years.manyoftheoriginalideasthatihavedevelopedoncertainissuesinmyfieldcannotbefullyputintopracticeonaccountofthelimitationsinpersonnel,experimentalfacilitiesandresearchfunds.consequently,istronglywishthaticanbeadmittedintoyouresteemeduniversitytoundertakeanadvanceddegreeprograminclinicalmedicine&gastroenterology.
ihavecherishedadeepandlongyearningforachancetostudyatyouruniversity.asearlyastheyearswheniwasanundergraduateatthedepartmentofmedicineof(provincial)medicaluniversity,ihadachancetoreadthebookthereachofhelicobacterpylorieditedbysomeprofessorsofyouruniversitywhichinfluencedmetotakeupthestudyofdigestivediseasesasmyareaofspecialization.later,duringmymaster’sprogram,ifocusedonthedevelopmentofthechronicstomachdisease(gastrosia)andtheincidenceofthegastriccancer.thecomprehensiveresearchandpracticethatihaveperformedinthisareafurtherreinforcemydeterminationtoseekadvancedstudiesatyouruniversitywhenthereshouldbeanopportunity.thisisbecauseyouresteemeduniversityenjoysaveryhighacademicreputationfortheresearchworkyouhavecarriedoutinthefieldofdigestivediseasestudy.thisensuresthatificanbeadmittedintoyourprogramiwillbepartofyourwell-respectedprogramandiwillbeabletoundertakein-depthstudyanddevelopacloseunderstandingofthemostupdatedtheoriesandtechnicaldevelopmentsinthisfield.byworkingtogetherandexchangingexperienceswiththeworld’sleadingexpertsinthisfield,iwillbeexposedtowhollynovelideasofresearchandsignificantlybroadenmyacademicvision.atthesametime,aschinaisacountrywithahighincidenceofhepatopathy(liverdisease),ibelievethaticanmakeimportantcontributionstotherelevantresearchprojectsofyouruniversitywithmyrichclinicalexperienceinthisfield.ofcourse,iamfullyawarethat,tobeabletoenrollinyourprestigiousandtime-honoreduniversity,iwillbeinevitablyconfrontedwithfiercecompetitionsfromotherelitiststudentstheworldover.butihavefullconfidenceinmyselfasaworthycandidateforyourprogrambasedonmypasteducation,researchandclinicalexperience,aswellasmyaspirationtodevelopmyselfintoaleadingexpertinchinainmychosenarea.
atthedepartmentofmedicineandthegraduateschoolofmedicaluniversity,irespectivelycompletedmybachelor’sprogramandmymaster’sprogramininternalmedicine.throughmyacademicendeavors,ihavenotonlylaidafirmyetcomprehensivegroundworkinmedicaltheories,becomingwell-readinclassicmedicalliterature,butalsodevelopedasoundabilityinrigorousyetflexiblelogicalthinkingandasenseofscientificcommitment.iamrelativelystrongatprobing,fromamicroperspective,intotheetiopathologicanddevelopmentalmechanisms,attheoreticallydeducingtheprocessofthegenesisofapathologicalstate,andatdemonstratingitthroughwell-designedexperiments.duringheatedclassroomdiscussions,icouldalwaysconvincemyclassmateswithmyeloquentpresentation,rigorouslogicalanalysisanddetailedexperimentalstatistics.inadditiontothat,ihavealsowongeneralrecognitionfromtheteachersandprofessorswhotaughtme.myresearchcapacity,creativethinkingandexperimentalskillsexperiencedfurtherimprovementasijoinedaresearchgroupattheresearchinstituteofdigestivediseasestoundertakearesearchprojectformymaster’sprogram.undertheleadershipofprof.,themostcelebratedspecialistondigestion,iparticipatedintheprojectthedevelopmentofchronicstomachdisease(gastrosia)&themechanismofcancerizationsponsoredbyprovincialbureauofpublichealth.inthisproject,ifocusedmyresearchonthemechanismofactionandthecellularimmunityofthecatalystsubunittelomeraseincancerizationandinvestigated,throughamicroscopicapproach,theclinicalsignificancethatthosetwofactorsmayproduceonthediagnosis,treatmentandprognosisofthegastriccancer.mythesis,entitledtheexpressionofhtertmrnaandcellularimmunityingastriccancerandprecancerosiswonhighevaluationsfromprof.andprof.andotherspecialistsfromunionhospitalandtheno.1clinicalmedicalinstituteofuniversity.theyratedmythesisas“demonstratingoriginalityinconceptionandeffectivemethodology,enrichingrelevanttheoriesandhavingmarkedclinicalsignificance.”
ihaveaccumulatedmuchpracticalclinicalexperiencesinceistartedworkingattheno.2hospitalofmedicaluniversitywhichisclassifiedasthe“grade-aclass-iii”hospital(thehighestrankingforahospitalinchina).basedonmyresearchduringthemaster’sprogram,iexpandedmyresearchareatoincludethestudyongastriccancer.ihavepublishedatotalofsixpapers(pleaserefertomyresumeformoredetailedinformation),includingthelatesttheexpressionandtheclinicalimplicationofthecatalystsubunittelomeraseingastriccancerandprecancerosis,intheworldjournalofgastroenterologyandotherleadingjournalsinchinaandcollectedintosciencecitationindex-expandedindexmedicus/medlineandchemicalabstracts.someofthosepapersweredesignatedtobepresentedatannualconferenceondigestioninandprovince.whileundertakingresearch,ihavereceivedformalandcomprehensivetrainingasresidentphysicianofinternalmedicineandobtainednationaldoctorlicense.throughthetrainingprogramihavegraspedthepathogeneticmechanismsofgastrointestinalandliverdiseases,cardiovasculardiseases,endocrinopathy,pulimonaryandconnectivtissuediseasesandtheircorrespondingdiagnosisandtreatment.inlessthantwoyearsafterworkingatthehospital,ipassedthenational-levelqualifyingexaminationtohaveachievedthequalificationsasthephysician-in-chargeindigestiveinternalmedicine.
helicobacterpylorihasbeenregardedasthekeyfactorintheincidenceofgastricdiseasesandthecontributingfactorincancerization.theresearchinthisfieldhasreachedthemolecularlevel.ihaveagoodfoundationofacademicresearchinthisaspect.chinahasahighincidenceofliverdiseasesandalargeproportionofpatientsidealwithinmydailyworkarethoseofhepatitis,allowingmetoacquireabundanceclinicalexperienceanddeepunderstandingconcerningthegenesisofthehepatitisandthedisease-causingmechanismoftheviruses.thosetwofieldswillbetheareaoffocusinmyprospectiveprogramatyouruniversity.ideally,ihopetoachievesomebreakthroughtheoreticallyandtechnically.fortoomanytimes,ihavewitnessedtheenfeeblementoftheotherwiserobustlifeofpatientsduetotheirphysiologicalconditions.thehorrorofseeingthegradualdwindlingofastrong-willedlifeissimplybeyonddescription.butihavelargelytransmutedthishorrorintoamotivationbehindallmyacademicendeavorsandprofessionalpractices.forme,successhasonlyonemeaning,thatis,tounravelthemysteriesofthediseasespesteringhumanbeingsandtocontributetothewell-beingofmypatients.